Marine arthropod lectins are proteins that bind specifically to carbohydrates and have the potential for a variety of biological and medical applications. As a leader in the field of marine glycobiology, CD BioGlyco is equipped with a wide range of advanced analytical tools and offers a comprehensive arthropod-derived lectin production service. We ensure the production of high-quality Marine Lectins for biotechnology and medical research or potential applications.
We are constantly updating our technology for Marine Biomolecule Production to provide high-quality, customized production services for a range of scientific studies. Advanced technology and deep research into lectins ensure that we purify lectins efficiently and gain insight into their characteristics. Our Marine arthropod-derived lectin production is suitable for a wide range of species, including shrimp, crabs, etc. The process is described below:
This process involves extracting hemolymph from arthropods such as crabs, lobsters, shrimp, etc., and then centrifuging to remove most impurities.
We use affinity chromatography to capture and purify the lectin from the crude extract.
Purified lectins are characterized to determine their molecular weight, amino acid composition, carbohydrate-binding properties, secondary structure, and biological activity.
Our experienced researchers develop tailored production protocols based on specific needs and ensure the structural integrity and biological activity of arthropod-derived lectins.
Technology: Affinity chromatography
Journal: Marine Drugs
IF: 5.4
Published: 2022
Results: This study describes the types, purification methods, and some biological activities of lectins from marine arthropod sources. C-type lectins and mannose-binding lectins have been isolated from shrimp and others. Affinity chromatography is a method commonly used for purifying lectins of marine arthropod origin. They were found to have good antibacterial activity, immunomodulatory activity, and potential applications in the fields of biomedicine and pharmaceuticals.
What is the focus of research on marine arthropod C-type lectins?
C-type lectins are a superfamily of proteins that require the involvement of calcium ions to selectively bind sugars. Studies on marine arthropod C-type lectins have focused on shrimp, including structural characterization, expression patterns, immune functions, etc. The expression patterns of arthropod C-type lectins are found to be similar, and most of the C-type lectins are expressed in immune tissues and organs at significantly higher levels than in other tissues and organs. C-type lectins are also involved in a variety of immune responses, such as agglutination, bacterial inhibition, and participation in signaling pathways. The combination of gene editing, biochemical technologies, etc. helps to gain insights into the specific in vivo functions and potential applications of C-type lectins, among others.
Can marine arthropod-derived lectins be used in anti-cancer research?
Marine arthropod-derived lectins have specific carbohydrate-binding properties. They may bind to sugar complexes on the surface of cancer cells and produce certain anti-cancer effects. They may also act as drug delivery carriers to deliver anti-cancer drugs to cancer cells and increase anti-cancer efficacy.
CD BioGlyco provides a high-quality arthropod-derived lectin production service to help unlock the value of their applications. We are always at the forefront of marine glycobiology and provide innovative solutions and high-quality products. Welcome to
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