Marine Carbohydrate-based Adjuvant Development Service at CD BioGlyco
Compounds with polysaccharide structures extracted from marine organisms have immune-enhancing effects and can promote the activation and proliferation of immune cells, thereby improving the immunization effect of vaccines. At present, marine carbohydrate-based adjuvant development has become one of the hot spots in the field of vaccine research. CD BioGlyco is a leading company focusing on research of marine carbohydrates. Our primary focus revolves around offering exceptional Marine Carbohydrate-based Vaccine and adjuvant development services. We are dedicated to providing innovative and effective marine carbohydrate-based adjuvant development solutions to clients globally, ensuring their utmost satisfaction.
Sargassum pallidum polysaccharide has shown potential in biopharmaceutical research, CD BioGlyco is well-equipped to support the development of Sargassum pallidum polysaccharide adjuvant.
With a wealth of expertise and comprehensive services, CD BioGlyco stands at the forefront of the industry in providing α-galactosylceramide adjuvant development services.
Our expertise is specialized in the field of marine glycan research. We are dedicated to providing exceptional deacetylated chitin adjuvant development services to our clients.
As a leader marine carbohydrate research, CD BioGlyco boasts a diverse range of technical approaches in the development of dihydroxypropyl-chitosan adjuvant, providing one-stop solution to our clients.
Our team of experts is committed to providing free consultation to ensure that each client's unique needs are met with tailored glycated chitosan adjuvant development solutions.
At CD BioGlyco, we take pride in our ability to deliver fast, accurate, and cost-effective λ-carrageenan adjuvant development services. We assist clients in optimizing the properties and efficacy of λ-carrageenan adjuvants, ultimately enhancing their overall project outcomes.
Our commitment to providing α-galactosylceramide-derived adjuvant development service has earned us a reputation as a trusted partner among thousands of researchers worldwide.
We pride ourselves on our ability to deliver innovative heparin derivative adjuvant development solutions that meet the unique needs of each client while adhering to the highest standards of quality and reliability.
As the leader in independent biotechnology, CD BioGlyco has attracted a vast network of researchers and partners from all around the world to provide professional D-glucosamine adjuvant development services to clients.
Typically, we select suitable marine organisms to extract the compound or get the target molecule through chemical synthesis. After optimizing the structure of the molecule, we carry out steps such as purification and characterization, functional evaluation, formulation optimization, application validation, safety assessment, and production process development. We customize these steps according to your specific needs, and we also provide you with efficient and high-quality adjuvant R&D services using our professional technologies, including high-performance liquid chromatography (HPLC), gel filtration chromatography (GFC), ultraviolet spectroscopy (UV), nuclear magnetic resonance (NMR), dynamic light scattering (DLS), differential scanning calorimetry (DSC), toxicity assessment, and pharmacological property assessment.
Fig.1 Major steps of marine carbohydrate adjuvant development. (CD BioGlyco)
Publication Data
Technology: Marine biological extraction technology
Journal: Biomolecules
IF: 6.064
Published: 2019
Results: The central conclusion of this paper is that vaccine adjuvants derived from marine organisms have potential immune-enhancing effects and have had some practical applications in medical immunology and veterinary medicine. However, there are currently only two adjuvants obtained from marine organisms that have been approved for use in commercial vaccines, and their application is restricted to anti-influenza vaccines. Future research will be devoted to finding and licensing new immunostimulatory substances and expanding their applications. Furthermore, upcoming adjuvants ought to incorporate ligands that can interact with pattern recognition receptors (PRRs), particularly Toll-like receptors (TLRs) and NOD-like receptors (NLRs). This will help regulate the polarization of Th1/Th2 in the adaptive immune response and enhance both the speed and potency of the immune response.
Fig.2 Putative mechanisms of action of the adjuvants. (Sanina, 2019)
Applications
- Seaweed polysaccharide adjuvants are used to activate and regulate the immune system, promote apoptosis of tumor cells and clearance of cancer cells, and therefore have been applied in immunotherapy research.
- Marine sugar adjuvants increase the solubility and stability of drugs, thereby improving their bioavailability and efficacy.
- Algae polysaccharide adjuvants are used to prepare highly sensitive biosensors for the detection of various biomolecules.
Advantages
- Marine carbohydrates typically have low toxicity and are biocompatible to the human body.
- We have a great variety of marine carbohydrate-based adjuvant development services, making it possible for you to choose the most suitable sugar compound as an adjuvant according to your needs.
- We offer our services to a team of experienced professionals with expertise and know-how in adjuvant development in the field of marine glycoconjugates.
CD BioGlyco boasts highly skilled teams dedicated to the development marine carbohydrate-based adjuvants. With a repertoire of cutting-edge technologies, we assist clients in advancing the comprehensive development of carbohydrate-based adjuvants on a global scale. If you would like more information about our services, please feel free to contact us.
Reference
- Sanina, N. Vaccine adjuvants derived from marine organisms. Biomolecules. 2019, 9(8): 340.
