Glycooxidation-related Product Biomarker Development Service

Glycooxidation-related Product Biomarker Development Service at CD BioGlyco

With marine-derived carbohydrates being of particular interest, the naturally occurring, non-enzymatic reaction between glucose and N-terminal and lysine residues, known as protein glycation, becomes key. This process yields early-stage glycation adducts and glycation end products (AGEs), with implications on metabolic functions. Certain glycation end products, when found in elevated levels, are associated with aging and diseases such as diabetes. At CD BioGlyco, we provide comprehensive Biomarker Development Services built upon a profound understanding of protein glycation in Marine-derived Carbohydrates, opening up new paths to elucidate disease mechanisms and explore potential therapeutic approaches.

Fig.1 The formation of the endogenous AGEs. (Boșca, et al., 2022)

We offer the glycooxidation-related product biomarker development service, an advanced solution for unraveling the complexities of glycooxidation processes. With our state-of-the-art techniques and expert scientists, we facilitate comprehensive Analysis and understanding of glycooxidation-related products. Our strategies help identify potential biomarkers linked with various conditions such as diabetes and aging, providing useful insights for therapeutic strategy development.

Here is our standard development process

• Firstly, our researchers discuss with clients the particular needs of the project. Critical aspects such as the samples to be studied, their origins, and the preferred analytical techniques are sorted out during this stage.
• After a comprehensive consultation, the client provides the samples that should be analyzed. The samples could come from various sources and their preparation might require particular procedures, depending on the client's requirements.
• The samples undergo the necessary preprocessing steps, which may involve cleanup, concentration, or other modifications to get them ready for analysis.
• The prepared samples are then analyzed using cutting-edge equipment and advanced methods at CD BioGlyco. The analysis method depends on the biomarker being investigated. CD BioGlyco offers a wide variety of screening and detection options. The produced data is interpreted by experienced specialists who draw meaningful conclusions from the complex raw data.
• After the analysis and interpretation, CD BioGlyco generates a detailed report.

Fig.2 Some of our analysis methods used for biomarker development. (CD BioGlyco)

Publication

Technology: AI machine learning, Precision medicine

Journal: Redox Biology

IF: 11.4

Published: 2021

Results: Protein glycation, specifically glycated hemoglobin or A1C, serves as a key biomarker for diagnosing diabetes and prediabetes, as well as measuring glycemic control. A similar biomarker, glycated albumin, also indicates glycemic control. Applications of glycation biomarkers are being further developed by AI machine learning, extending their potential use to healthy aging and early-stage arthritis diagnosis, among others. They are likely to be increasingly used in precision medicine. Technologies used include artificial intelligence and machine learning.

Fig.3 Biomarkers of glycation in clinical use research and investigational development. (Rabbani & Thornalley, 2021)

Applications

• Identification of glycooxidation-related biomarkers for diseases such as diabetes, neurodegenerative disorders, and cardiovascular diseases.
• Assessment of glycooxidative stress as a potential target for drug development.
• Understanding the role of glycooxidation in cellular processes and disease pathways.

Advantages

• At CD BioGlyco, our team specializes in glycooxidation-related product biomarker development, ensuring in-depth knowledge and proficiency in this specific area.
• CD BioGlyco offers a comprehensive suite of services for glycooxidation-related product biomarker development, covering everything from sample preparation to detailed data analysis.
• CD BioGlyco provides customized solutions based on the unique requirements of each project, ensuring that clients receive tailored strategies that align with their objectives.

CD BioGlyco stands out as a reliable partner for glycooxidation-related product biomarker development, offering a combination of specialized expertise, innovative approaches, and a commitment to delivering high-quality results. Please feel free to contact us if you are interested in our custom services.