Pure Marine Polysaccharides, Maximum Benefits
At CD BioGlyco, we employ a range of outstanding technologies to purify marine polysaccharides, particularly focusing on the valuable compounds laminarin and fucoidan from macroalgae. Based on our Marine Carbohydrate Production Service, you find many marine polysaccharides and these polysaccharides have significant industrial applications due to their diverse biological activities, including anti-inflammatory, anticoagulant, antioxidant, antiviral, antitumor, and immunostimulatory effects. Our purification technologies isolate and purify marine polysaccharides, each technique is based on different principles, allowing us to achieve high purity and retain the bioactive properties of these Valuable Marine Compounds.
Fig.1 Range of marine polysaccharides available. (Barbosa, et al., 2019)
Our full suite of purification techniques, including chromatography, precipitation, zonal electrophoresis, salting out, metal coordination, ultracentrifugation, membrane filtration, and preparative gel electrophoresis, allow us to carefully isolate and refine polysaccharides from marine plants and animals.
Chromatography Purification of Marine Polysaccharides
Chromatography techniques are used to separate and purify polysaccharides based on their size, charge, and affinity properties. This method ensures high purity and specificity, which is critical for detailed structural and functional studies.
Salting-out Purification of Marine Polysaccharides
Salting-out involves adding salts to reduce the solubility of polysaccharides, causing them to precipitate. This method is effective for concentrating and purifying polysaccharides from aqueous solutions.
Publication Data
DOI: https://doi.org/10.3390/md17120654
Technology: Nanoparticle formation, Chemical modifications, Solvent extraction, Ultrasonication, Microwave-assisted extraction, Enzyme-assisted extraction
Journal: Marine Drugs
IF: 5.4
Published: 2019
Results: This review highlights the significant role of marine polysaccharides, specifically fucoidan and chitosan, in pharmaceutical applications. These polysaccharides exhibit a wide range of biological activities such as anti-inflammatory, anticoagulant, antioxidant, antiviral, antitumor, and immunostimulatory effects, making them highly valuable for drug delivery systems. The study also underscores the importance of optimizing extraction and purification processes to enhance the yield and bioactivity of these compounds. Additionally, innovative methods such as nanoparticle formation and chemical modifications have been explored to improve the solubility, bioavailability, and therapeutic efficacy of marine polysaccharides.
Applications
- Purified polysaccharides like fucoidan and chitosan are utilized in developing drug delivery systems to enhance the bioavailability and therapeutic effectiveness of medications.
- Highly purified polysaccharides are used in dietary supplements to provide health benefits such as enhanced immune function and improved gut health.
- Purified polysaccharides are used to develop tissue engineering scaffolds to aid in tissue and organ regeneration.
Advantages
- Advanced purification technology ensures high purity of the extracted polysaccharides.
- Methods such as ultrasonic and microwave-assisted extraction improve the extraction efficiency of polysaccharides compared to traditional methods.
- Techniques such as ultrasonic and microwave-assisted extraction significantly increase the efficiency of extracting polysaccharides, offering improvements over traditional extraction methods.
- Many purification techniques, such as membrane filtration and ultracentrifugation, are environmentally friendly.
Frequently Asked Questions
What are marine polysaccharides, and why are they important?
Marine polysaccharides are intricate carbohydrates sourced from marine organisms, including seaweeds and crustaceans. These compounds are valued for their distinct biological properties, such as their ability to form gels, bind water, and interact with cells in specific ways. These unique features make marine polysaccharides particularly useful across a range of industries. In the medical field, marine polysaccharides are investigated for their potential uses in drug delivery systems, wound care, and as dietary supplements. In the food industry, they are used as natural thickeners, stabilizers, and emulsifiers to improve texture and extend shelf life.
What are the types of precipitation purification?
- Solvent precipitation: Adding solvents like ethanol or acetone.
- pH adjustment: Changing the pH to reach the isoelectric point of the polysaccharide.
- Temperature changes: Cooling the solution to precipitate polysaccharides.
CD BioGlyco provides high-quality marine polysaccharides that meet the demands of diverse industries, ensuring safety, efficacy, and sustainability in their applications. Please feel free to contact us for more information.
Reference
- Barbosa, A.I.; et al. Marine polysaccharides in pharmaceutical applications: Fucoidan and chitosan as key players in the drug delivery match field. Marine Drugs. 2019, 17(12): 654.
