Acanthifolioside Production Service

Join Us on the Path to Highly Active Acanthifolioside Production

Acanthifolioside is a minor steroidal saponin from the Caribbean marine sponge Pandaros acanthifolium. Our company is dedicated to extracting and producing high-quality Acanthifolioside to meet our clients' needs. CD BioGlyco has advanced production equipment and a professional team to ensure the purity and quality of our products. With the support of our Marine Biomolecule Production team, our lab provides professional Marine Glycoside Production services.

Sample Preparation

As a professional glycobiology company, we care a lot about the collection and pretreatment of raw materials. Our researchers use deionized water or seawater to rinse the sponge samples to remove sediment and impurities on the surface. According to the experimental needs, the samples are cut into the appropriate amount of blocks. The sponge is kept frozen from collection until the extraction process.

Extraction and Isolation of Acanthifolioside

Schematic diagram of commonly used separation techniques. (CD BioGlyco)

Organic Solution Extraction: Our researchers use solvents to extract the chopped samples and dissolve the extracts into the solvents. We obtain the concentrated extract by concentration and evaporation. Moreover, our research team has optimized the actual concentration of crowding, extraction time, and temperature to achieve high-quality deliveries.
Purification: For crude extracts, our specialized glycoside separation team uses a variety of chromatographic and elution solutions to separate the target components.
❏Reversed-phase (RP)-C₁₈ flash chromatography
❏Semi-preparative chromatography
❏High-performance liquid chromatography (HPLC)
❏Thin layer chromatography (TLC)

Structural Characterization

We deliver product reports with HPLC analysis, nuclear magnetic resonance (NMR) analysis, gas chromatography analysis, and mass spectrometry (MS) analysis. If you have other needs for characterization, let us know at the first time.

Activity Evaluation

We mainly provide antiprotozoal assay and cytotoxicity assay services. We have experienced scientists to plan the whole production program for you to deliver good products with high quality and purity.

Flowchart of acanthifolioside production. (CD BioGlyco)

Applications

Acanthifolioside has a wide range of biological activities and potential medicinal values for improving immune system functions.

Acanthifolioside has inhibitory effects on a wide range of bacteria and fungi play a role in the treatment of infectious diseases or the prevention of bacterial infections.

Advantages of Us

According to the different needs of clients, we provide acanthifolioside and acanthifolioside methyl ester.

Our trusted production team ensures that marine sponge samples maintain their biochemical properties during processing and storage, thereby increasing the accuracy and reliability of subsequent experiments.

During the extraction process, our lab uses organic reagents for multiple extractions to maximize the dissolution of the extract in the reagents.

The entire process requires care to keep the operating environment clean and the materials pure, and we ensure that the extraction and separation results are optimized.

Frequently Asked Questions

What are the structural differences between acanthifolioside A-F?

Firstly, acanthifolioside A-C contain mono-β-D-xylopyranosides, acanthifoliosides D and E contain mono-α-L-rhamnopyranosides, whereas acanthifolioside F has a branched triglycoside carbohydrate chain. Secondly, the carbohydrate chains are connected in different positions. For example, acanthifolioside A-C is attached to C-15, and acanthifolioside D-F is attached to C-16.

What are the main biological activities of acanthifolioside?

Acanthifoliosides have antiprotozoal activity and inhibit the growth of Leishmania donovani and T. brucei rhodesiense.

CD BioGlyco achieves efficient production of acanthifoliosides by combining various separation techniques. The production of high-purity and high-stability glycosides further promotes the innovation and application of biotechnology and expands the development of marine organisms in areas such as biomedicine. Whatever concerns you have about acanthifolioside production, please feel free to contact us.

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