Unlock the Value of Lectins Through High-quality Mollusk-derived Lectin Production Service
Mollusks are found to contain a variety of lectins with important applications in bioprocess research, biomedicine, and other fields. Based on our rich experience and cutting-edge technology in Marine Biomolecule Production, CD BioGlyco provides a mollusk-derived lectin production service. We aim to help our clients explore the application value of Marine Lectins through high-quality lectins.
Our mollusk-derived lectin production service is available for clams, scallops, oysters, etc. Lectin production protocols may vary from source to source. Our experienced specialists develop individualized production protocols based on client-specific purposes and sample types. The production steps are as follows:
Extraction and purification of mollusk-derived lectin
This process involves the acquisition and isolation of a crude extract of lectin. We combine a variety of purification methods to ensure the high purity of mollusk-derived lectin, including affinity chromatography, ion-exchange chromatography, and gel filtration chromatography.
Characterization of mollusk-derived lectin
We have advanced equipment to characterize mollusk-derived lectin such as an amino acid autoanalyzer, mass spectrometry, etc. Amino acid composition analysis, secondary structure detection, etc., are done.
- Sodium dodecyl-sulfate polyacrylamide gel electrophoresis (SDS-PAGE) is used to detect the molecular weight of lectins.
- Mollusk-derived lectin carbohydrate specificity is analyzed by hemagglutination inhibition test.
- Amino acid composition is detected by amino acid autoanalyzer and mass spectrometry.
- The secondary structure is analyzed by circular dichroism.
In addition to high-quality lectin production services, we also provide our clients with comprehensive research guidance in different fields.
Publication Data
Technology: Affinity chromatography, SDS-PAGE, mass spectrometry
Journal: Marine Drugs
IF: 6.085
Published: 2021
Results: In this study, a novel lectin (CYL) was isolated from Glycymeris yessoensis by affinity chromatography. Structural characterization revealed that CYL consists of subunits linked by disulfide bonds and is a dimeric protein, dominated by the β structure. CYL was shown to have an unusual carbohydrate specificity by hemagglutination inhibition test results. The microbial binding activity of CYL suggests its potential use in antimicrobial applications. This study provides theoretical support for the purification and characterization of molluscan lectins.
Fig.1 Purification results of CYL. (Mizgina, et al., 2021)
Applications
- Cell biology: Mollusk-derived lectins are a valuable tool for studying intermolecular interactions, recognition, etc.
- Biomedicine: Mollusk-derived lectins have potential applications in drug delivery systems, targeted therapies, and more.
- Diagnostic tools: Mollusk-derived lectins are used to detect specific carbohydrate structures, contributing to disease research.
Advantages
- One-stop service: We provide one-stop service from method development, lectin extraction, and purification, to characterization.
- Customized solutions: We provide tailor-made lectin production solutions to meet the specific needs of our clients.
- High-quality products: We optimize the mollusk lectin production process and ensure the purity and consistency of each batch.
Frequently Asked Questions
Which mollusks produce lectins?
Certain species of mollusks have been identified as sources of lectins, such as clams, scallops, oysters, and abalone. They have different carbohydrate specificities and rich biological properties with potential applications in biomedicine, biomaterials development, and more.
What are the biological activities of mollusk lectins?
Many lectins with different carbohydrate specificities have been purified from mollusks and their biological properties have been characterized. They have been found to have immunomodulatory functions, anti-inflammatory, antibacterial, anti-HIV activity, anticancer properties, etc., and have been used in studying antimicrobial agents, modulation of immune activity, and detection of specific carbohydrate molecules.
CD BioGlyco remains at the forefront of marine glycobiology research and provides reliable services. We utilize cutting-edge technology in marine lectin production and characterization to provide innovative solutions to our clients. Please feel free to contact us to discuss further details of mollusk-derived lectin production if you need this area.
Reference
- Mizgina, T.O.; et al. Identification and characterization of a novel lectin from the Clam Glycymeris yessoensis and its functional characterization under microbial stimulation and environmental stress. Marine Drugs. 2021, 19(9): 474.
