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Carrageenan Characterization Service

Carrageenan Characterization Service

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Unlocking the Full Potential of Carrageenan: From Extraction to Bioactivity Analysis!

At CD Bioglyco, we provide one-stop services such as the Production, Characterization, and Bioactivity Analysis of marine carbohydrates to unlock the development and application of marine carbohydrates. Carrageenan is a sulfated polysaccharide extracted from red algae. Its excellent gelling, thickening, and stabilizing properties make it widely used in industry. We provide clients with carrageenan extraction, purification, characterization, and bioactivity analysis services.

Carrageenan Extraction

We use advanced technologies to extract natural carrageenan polysaccharides from various red algae. Commonly used technologies include ultrasound-assisted extraction, microwave-assisted extraction, and supercritical fluid extraction. Ultrasonic-assisted extraction uses ultrasound to improve extraction efficiency and reduce processing time. Microwave-assisted extraction uses microwaves to accelerate the healing process in extraction, thereby increasing yield and reducing energy use. Supercritical fluid extraction uses supercritical CO2 to extract carrageenan more efficiently and sustainably.

Precipitation and Purification of Carrageenan

We precipitate carrageenan from solution using isopropyl alcohol or by adding salts, such as potassium salts or ethanol for kappa (κ) carrageenan, calcium salts for iota carrageenan (ι), and ethanol for lambda carrageenan (λ). The precipitated carrageenan is then separated by centrifugation and washed several times with alcohol or water to remove residual salts and impurities. The purified carrageenan is dried to obtain a powder form, and the drying conditions are carefully controlled to maintain its functional properties. We also further purify the carrageenan by repeated filtration, ion exchange, and dialysis to obtain a highly pure product.

Carrageenan Characterization

Fourier transform infrared spectroscopy (FTIR) and nuclear magnetic resonance (NMR) are used to analyze the functional groups and molecular structure of carrageenan. High-performance liquid chromatography (HPLC) is used to measure the purity and molecular weight distribution of carrageenan. Rheology is used to evaluate the gel strength, viscosity, and other mechanical properties of carrageenan. Differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) are used to evaluate the thermal properties of carrageenan, such as melting temperature and thermal stability. We also perform elemental analysis on samples.

Bioactivity Analysis of Carrageenan

Bioactivity analysis of carrageenan is essential to understand its potential health benefits, therapeutic properties, and stability under different conditions. We offer carrageenan anticoagulant activity analysis, anti-inflammatory property analysis, antiviral activity assays, antimicrobial assays, and antitumor activity analysis.

Characterization and activity analysis of carrageenan. (CD BioGlyco)

Publication

Technology: FTIR,1H NMR,31P NMR,Scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDX)

Journal: Plos one

IF: 2.9

Published: 2017

Results: The authors modified and characterized the polymer electrolyte membrane of the natural polymer κ-carrageenan. First, O-methylene phosphonic κ-carrageenan (OMPC) was successfully synthesized by phosphorylation of κ-carrageenan using formaldehyde and phosphorous acid. The chemical structure of OMPC was then characterized by FTIR, 1H NMR, 31P NMR, and SEM-EDX. The authors also measured the impedance spectra of κ-carrageenan and OMPC in dry and hydrated states to study the conductive properties of the membrane. The results show that the ionic conductivity of OMPC is higher than that of κ-carrageenan, and the ionic conductivity of the hydrated membrane is two orders of magnitude higher than that of the dry membrane.

Fig.1 1H NMR spectra of (a) κ-carrageenan and (b) O-methylene phosphonic κ-carrageenan (OMPC).Fig.1 1H NMR spectra of (a) κ-carrageenan and (b) OMPC. (Liew, et al., 2017)

Applications

  • Detailed characterization services help analyze the viscosity and gel strength of carrageenan to ensure the texture and stability required in the food.
  • Carrageenan is used to develop drug-conveying materials, and detailed characterization services help evaluate biocompatibility and biodegradability.
  • Carrageenan is used for the cell culture system, and the characterization service is used to study the impact of carrageenan on the process of microbial culture and fermentation.
  • Carrageenan characterization service is used to evaluate the consistency of the quality and performance of different batches of cosmetics.

Advantages of Us

  • We use high-end precision instruments and our laboratory personnel undergo rigorous training and examinations to ensure data accuracy and reproducibility.
  • Our characterization services are suitable for both small-scale academic research and large-scale industrial projects.
  • Our carrageenan characterization services cover all aspects from molecular structure analysis to functional performance determination to ensure that researchers and manufacturers understand the physical, chemical, and functional properties of materials, which is critical for product development, quality control, and cutting-edge research.
  • Our optimized sample processing process minimizes sample volume requirements without sacrificing data quality.

Frequently Asked Questions

Can the characterization service identify the type of carrageenan?

Yes, we accurately identify and differentiate the different types: κ-carrageenan, ι-carrageenan and λ-carrageenan. For example, using FTIR to identify the specific functional bonds inherent in each type of carrageenan, using NMR to achieve precise identification of the carrageenan type, and using HPLC to separate and identify different types of carrageenan based on their retention time.

What industries are carrageenan characterization services suitable for?

Carrageenan's gelling, thickening, and stabilizing properties make it very versatile, so our characterization services apply to any industry containing carrageenan, including food and beverage, pharmaceuticals, cosmetics, agriculture, and biotechnology.

At CD BioGlyco, we use a range of advanced analytical techniques to determine the molecular structure, composition, and functional properties of different types of carrageenan. Please feel free to contact us for more information on carrageenan analysis.

Reference

  1. Liew, J.W.Y.; et al. Synthesis and characterization of modified κ-carrageenan for enhanced proton conductivity as polymer electrolyte membrane. Plos one. 2017, 12(9): e0185313.
For research use only. Not intended for any clinical use.
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  • SUITE 201, 17 Ramsey Road, Shirley, NY 11967, USA
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