Marine Glycoconjugate Development Service

Marine Glycoconjugate Development Service at CD BioGlyco

Marine glycoconjugates are natural compounds extracted from marine organisms and have diverse structures and activities. Through in-depth research and development of marine glycoconjugates, we discover new chemical structures and active compounds, which are of great significance to drug development, bioengineering, the food industry, and other fields. CD BioGlyco has accumulated rich experience in providing clients with high-quality marine glycoconjugate development. Our services are comprehensive, diversified, and professional.

• Marine Glycoconjugates Screening and Identification Service: We screen libraries of marine glycoconjugates for compounds with specific functions or activities through high-throughput screening techniques.
• Marine Glycoconjugation Service: Marine glycoconjugates play important biological functions in organisms, such as cell recognition, signal transduction, and immune responses. Our expert team provides various types of marine glycoconjugation services, such as glycoprotein conjugation, glycopeptide conjugation, glycolipid conjugation, etc.
• Marine Glycoconjugate Synthesis and Modification Service: Based on client needs, we provide professional chemical synthesis or structural modification for known marine glycoconjugates to change their properties, enhance activity, or improve pharmacokinetic properties.
• Marine Glycoconjugate Profiling Service: Marine glycoconjugates have huge structural and functional diversity. We provide diversified marine glycoconjugate profiling services to in-depth understanding of their types, structures, and functions, such as lectin histochemistry, omics analysis, etc.
• Marine Glycoconjugate Characterization Service: For marine glycoconjugate samples that need to be characterized, we provide efficient extraction, purification, and characterization services. We use various sophisticated analytical techniques (such as chromatography, mass spectrometry, nuclear magnetic resonance, etc.) to separate and extract marine glycoconjugates, characterize the structure of each glycoconjugate, and determine its molecular structure, glycosyl modification pattern, and other chemical characteristic.
• Marine Glycoconjugate Assessment Service: We evaluate the functions and activities of marine glycoconjugates through in vitro and in vivo assays, such as antioxidant, anti-inflammatory, antibacterial, etc. We also provide safety assessments for marine glycoconjugates, such as toxicological tests, to ensure their safety during application.
• Marine Glycoconjugate Production Service: We provide large-scale marine glycoconjugate production service and produce high-quality glycoconjugates by developing and optimizing production processes to meet commercial needs.

In addition, CD BioGlyco, as a biotechnology company specializing in the study of marine sugars, also provides Marine Glycomics and Glycoproteomics services. Moreover, we also provide diversified marine carbohydrates-based Drug-Delivery Vehicle Development Service and Biomaterial Engineering Development Service.

Fig.1 One-stop marine glycoconjugate development service. (CD BioGlyco)

Publication

Technology: A coagulometer and nuclear magnetic resonance (NMR) analysis

Journal: Marine Drugs

IF: 6.085

Published: 2012

Results: Fucosylated chondroitin sulfate (FuCS) was a complex glycosaminoglycan extracted from sea cucumbers that had high anticoagulant properties. The authors prepared O-acylated derivatives of depolymerized FuCS fragments and characterized the structures of the synthesized derivatives by NMR technology. In addition, the anticoagulant activity of the synthetic derivatives was also tested, and the results showed that the O-acylated derivatives of FuCS all had significant anticoagulant activity, and the activity was proportional to the molecular weight.

Fig.2 Effect of acylation on the anticoagulant activity. (Gao, et al., 2012)

Applications

• Drug development: Marine glycoconjugates have broad application potential in drug development. By analyzing and studying glycoconjugates in marine organisms, new active compounds are discovered and further carried out in drug design, optimization, and screening. Marine glycoconjugates are used as candidates for novel drugs such as targeted drug delivery systems, antibacterial agents, and antitumor drugs.
• Bioengineering: Marine glycoconjugates are used for the assembly and modification of biological materials for the preparation of biocompatible materials and biosensors.
• Food research: Marine glycoconjugates are used as additives, stabilizers, and nutritional supplements in food research, which improve the texture, stability, and mouthfeel of foods. Marine glycoconjugates are also used to develop functional foods such as antioxidants, anti-inflammatory agents, and immune modulators.

Advantages

• CD BioGlyco has world-class technical teams providing high-level marine glycoconjugate development services.
• CD BioGlyco has diversified technologies for marine glycoconjugate analysis to accurately and reliably analyze and characterize the structure and properties of marine glycoconjugates.
• CD BioGlyco provides high-quality marine glycoconjugate development service, provides custom solutions according to client needs, and ensures projects are delivered on time and with high quality.

CD BioGlyco has a rich marine biological resource library and collection capabilities, which obtain diverse marine biological samples as development objects. Our expert team provides cutting-edge marine glycoconjugate development services and explores new marine glycoconjugate development directions and application areas, including discovering new glycoconjugates and optimizing research methods. Please feel free to contact us if you need consultation for specific development details.