Marine Capsular Polysaccharide-based Biomaterial Engineering Development Service at CD BioGlyco
CD BioGlyco continues to develop Biomaterials Engineering Research Based on Marine Carbohydrates. Marine capsular polysaccharide is a heteropolymer or homopolymer produced by various marine organisms. It consists of repeating sugar units linked by glycosidic bonds. To better serve our clients, we offer biomaterial development services based on marine capsular polysaccharide applications.
Marine capsular polysaccharide is involved in a variety of biological functions such as cell adhesion, signaling, and defense mechanisms. We have been exploring the potential of marine capsular polysaccharide-based biomaterial engineering for various applications. Our development approach mainly includes the following:
Biocompatible scaffolds
Marine capsular polysaccharide is used as a biomaterial for tissue engineering scaffold development. Scaffolds based on marine capsular polysaccharides have a three-dimensional structure and are used to support cell attachment and tissue regeneration.
Drug delivery systems
We develop hydrogels and nanoparticles based on marine capsular polysaccharides. They have great potential for applications in encapsulating drugs, controlling drug release rates, and targeting specific sites.
Bio-adhesive materials
Marine capsular polysaccharide's adhesive properties promote strong bonding between tissues or biomaterials. Based on the adhesive properties of marine capsular polysaccharides, we develop bioadhesive materials for tissue adhesion.
Bone regeneration and biomineralization
Marine capsular polysaccharide has the ability to interact with calcium ions and other minerals. Based on this, we develop marine capsular polysaccharide-based biomaterials for biomineralization and bone regeneration. The biomaterial promotes the formation of mineralized tissues such as bone by enhancing the deposition of calcium minerals.
Bio ink
Marine capsular polysaccharide has the ability to support cell viability and function. We develop bio-inks based on marine capsular polysaccharides. This biomaterial is used to create tissue structures with enhanced functionality and biological relevance.
In addition, we also develop marine capsular polysaccharide-based biomaterials for use in biosensors, 3D bioprinting, and other applications.
Fig.1 Types of marine capsular polysaccharide-based biomaterials developed. (CD BioGlyco)
Publication Data
Technology: Modification
Journal: Annual Review of Microbiology
IF: 15.5
Published: 2020
Results: This paper describes the synthesis and assembly of extracellular polysaccharides, including capsular polysaccharides, and their potential applications. It was found that extracellular polysaccharides including capsular polysaccharides formed by synthase-dependent systemic assembly have potential applications in biomedical applications such as tissue engineering, drug delivery, and device coating.
Fig.2 Examples of synthase-dependent pathways and repetitive unit structures of EPSs assembled in this way. (Whitfield, et al., 2020)
Applications
- Biomaterials based on marine capsular polysaccharides are used to promote wound healing and tissue regeneration in burns, chronic wounds, etc.
- Biomaterials based on marine capsular polysaccharides have potential applications in plastic surgery and dental regenerative medicine.
- The developed marine capsular polysaccharide-based biomaterials are used for 3D bioprinting to achieve precise spatial alignment of cells, etc.
Highlights of Us
- We provide biomaterial development services for various applications.
- We optimize various experimental factors to improve the performance of marine capsular polysaccharide-based biomaterials and enhance their stability under different conditions.
- We fully exploit the potential of marine capsular polysaccharides for various applications in the fields of regenerative medicine, drug delivery, and diagnostics.
CD BioGlyco is relentless in its research efforts to optimize the properties of biomaterials based on marine capsular polysaccharides. Please feel free to contact us for inquiries regarding the development of biomaterials based on marine capsular polysaccharides. In addition to marine capsular polysaccharides, we also provide engineering development services for biomaterials based on Xylan, Heparan, Marine Peptidoglycan, and others. We are capable of realizing biomaterial development based on various marine carbohydrates.
References
- Kokoulin, M.S.; et al. Sulfated capsular polysaccharide from the marine bacterium Kangiella japonica inhibits T-47D cells growth in vitro. Carbohydrate Polymers. 2022, 290: 119477.
- Whitfield, C.; et al. Assembly of bacterial capsular polysaccharides and exopolysaccharides. Annual Review of Microbiology. 2020, 74: 521-543.
