Green Algae-related Biomarker Development Service at CD BioGlyco
Rare Sugar From Marine Green Macroalgae
Within Ulva sp., a type of green macroalgae, the valuable rare sugar L-rhamnose is found in the polymeric chain of ulvan. This sugar is linked with uronic acids (glucuronic and/or iduronic) to create aldobiouronic acid 4-O-β-D-glucuronosyl-L-rhamnose units. Additionally, Cladophora sp. has been identified as a source of psicose, also known as D-allulose or D-ribo-2-hexulose. Psicose possesses 70% of the sweetness of sucrose but only 0.3% of its calories. At CD BioGlyco, we harness the unique Polysaccharides present in green macroalgae for the production of these valuable rare sugars. Moreover, we also provide Custom Characterization Services for marine glycan for clients.
Fig.1 The structure of repeating disaccharide units of ulvan contained in green macroalgae Ulva sp. (Bayu, et al., 2021)
Green Algae-related Biomarkers Development Service
CD BioGlyco employs a comprehensive research process for the development of biomarkers related to green algae-based carbohydrates. Our research involves the exploration and analysis of polysaccharides derived from green algae, particularly focusing on their glycan structures and potential applications in biomarker development.
Fig.2 The process of green algae-related biomarkers development. (CD BioGlyco)
- We carefully choose green algae species known for their unique polysaccharide composition, ensuring diversity and richness in carbohydrate structures.
- We employ advanced extraction techniques to obtain high-quality polysaccharides from green algae.
- Utilizing cutting-edge analytical tools, we conduct an in-depth structural analysis of the extracted polysaccharides. This includes determining glycan linkages, monosaccharide compositions, and any unique features in the carbohydrate chains.
- Our researchers perform in vitro studies to assess the biological activities of green algae-derived carbohydrates. To validate the biomarker potential, we also conduct in vivo studies, assessing the impact of green algae-based carbohydrates on specific physiological processes, disease markers, or relevant health indicators.
- Through rigorous data analysis, we identify potential biomarkers associated with the use of green algae-based carbohydrates.
- At CD BioGlyco, our experienced team tailors solutions based on client needs. We offer customized biomarker development services, providing clients with valuable insights into the applications of green algae-based carbohydrates.
Our research process is characterized by a multidisciplinary approach, combining expertise in marine biology, biochemistry, and glycobiology to unlock the full potential of green algae-derived carbohydrates for biomarker development.
Publication
Technology: Raman spectroscopy, Mass spectrometry, Chromatography
Journal: Frontiers in nutrition
IF: 5
Published: 2022
Results: Microalgae is a sustainable source of prebiotics. Various techniques such as Raman spectroscopy, mass spectrometry, and chromatography were used to analyze the composition and characteristics of microalgae. These techniques can provide valuable insights into the bioactive compounds and potential applications of microalgae in various fields.
Fig.3 Presents the cycle of microalgae from their production to consumption in the human body and their potential benefits. (Gouda, et al., 2022)
Applications
- Identification of biomarkers associated with green algae-based carbohydrates can contribute to the development of diagnostic tools for specific diseases. These biomarkers may serve as indicators of disease progression, severity, or response to treatment.
- Understanding the impact of green algae-derived carbohydrates on metabolic pathways provides insights into their potential role in regulating metabolic processes.
- Green algae-based carbohydrates with beneficial effects on health can be explored for the development of nutraceuticals. These compounds may have applications in dietary supplements aimed at improving overall well-being and preventing or managing certain health conditions.
Advantages
- Based on our well-equipment and our outstanding professors, CD BioGlyco provides high-quality marine-derived glycan products and custom marine-related research solutions for clients worldwide.
- Biomarkers derived from algae-based carbohydrates are associated with health and wellness benefits, aligning with the growing consumer interest in natural and functional ingredients. This drives the development of products promoting overall well-being.
CD BioGlyco has established an a-level marine carbohydrate production platform that provides high-quality marine-derived glycan. Based on this, we provide the green algae-related biomarkers development service for clients. Please do not hesitate to contact us if you are interested in our services.
References
- Bayu, A.; et al. Macroalgae-derived rare sugars: Applications and catalytic synthesis. Carbon Resources Conversion. 2021, 4: 150-163.
- Gouda, M.; et al. Microalgae bioactive carbohydrates as a novel sustainable and eco-friendly source of prebiotics: emerging health functionality and recent technologies for extraction and detection. Frontiers in Nutrition. 2022, 9: 806692.
