Hemicellulose-based Film Development Service

Hemicellulose-based Film Development Service at CD BioGlyco

CD BioGlyco provides high-quality Marine Carbohydrate-based Material Development Services to meet client needs for drug delivery, bone tissue engineering, and more. Hemicellulose consists of sugars such as mannan, glucomannan, xylan, and xyloglucan. Hemicellulose, with its diverse structure, relatively low molecular weight, and ease of modification, offers a number of advantages in the preparation of thin films. We offer comprehensive development services for hemicellulose-based films.

• Hemicellulose-based Film Development Service
  We prepare hemicellulose-based flats by drying the film-forming solution on a mold, casting, and co-casting. We optimize the properties of the films by modifying the preparation conditions and modifying the hemicellulose according to client requirements. We maximize the barrier properties, flexibility, mechanical properties, biocompatibility, thermal stability, etc., of the films.

Fig.1 Process for the preparation of thin films based on hemicellulose. (CD BioGlyco)

• Modification of Hemicellulose
  Changes in the structure of hemicellulose affect the mechanical and thermal properties of hemicellulose-based films. We improve the properties of hemicellulose-based films by modification.
  • Chemical modification
    Hemicellulose has a large number of reactive groups such as carbonyl, hydroxyl, and carboxyl groups in its main and side chains. Using this as a reaction site, we modify a series of chemical reactions.
    • Esterification
      We increase the flexibility and hydrophobicity of hemicellulose membranes by replacing hydroxyl groups with hydrophobic esters through esterification.
    • Etherification
      Etherification is a reaction between an alkylating agent and an alcohol in the presence of a base. Our common alkylating agents include alkyl halides (iodides, bromides, and chlorides), epoxides, and alkyl sulfonates.
    • Graft modification
      We introduce functional groups into hemicellulose through graft polymerization to improve the properties required for certain applications. This increases solubility in organic solvents by reducing the formation of hydrogen bonding networks.
    • Crosslinking
      Modification by cross-linking provides the polymer with resistance to thermal degradation and improves resistance. Crosslinking reduces the solubility of hemicellulose in liquids and improves water resistance. Hemicellulose is crosslinked by chemical crosslinkers or radiation.
  • Physical modification
    We evenly distribute small molecules and/or polymers into the hemicellulose matrix. The composition and structure of the hemicellulose-based film are altered by non-chemical bonding, thereby improving its properties.

Publication Data

Technology: Solution casting method

Journal: Current Research in Green and Sustainable Chemistry

IF: 6.457

Published: 2020

Results: In the present study, hemicellulose-based films were prepared by solution casting method. Distilled water was mixed with hemicellulose. And 20, 40, 60, and 80 wt % content of hemicellulose was embedded in carboxymethyl cellulose (CMC). Finally, a H-CMC film with a thickness range of (0.076-0.12 mm) was successfully prepared. Characterization of the film showed that the best performance of the film was obtained at 60% of hemicellulose content. The films prepared in this study can be used as potential materials for green packaging applications.

Fig.2 Cross-sectional surface morphology for a) CMC, b) H-CMC-B, c) H-CMC-C, d) H-CMC-D, and e) H-CMC-E films. (Weerasooriya, et al., 2020)

Applications

• Hemicellulose-based films are used to develop wound dressings to extend the residence time of antibiotics in wounds and maintain a moist environment.
• Hemicellulose-based films replace petroleum-based materials for food packaging.
• Hemicellulose-based films are used for drug packaging or to prepare environmentally friendly materials.

Advantages of Us

• With our extensive experience in biomaterials development, we have a variety of experimental protocols for the preparation of hemicellulose-based films.
• We perform various optimizations of hemicellulose. Modified hemicellulose-based films will exhibit good flexibility, mechanical properties, and more.
• Our material development services include the modification and preparation of hemicellulose, evaluation of physical and chemical properties, cytological evaluation, and evaluation of animal experiments.

CD BioGlyco specializes in providing services and support for the development of biomedical-related materials. We have developed a variety of services for the modification, preparation, and physicochemical properties of materials based on marine carbohydrates. In addition to hemicellulose, we also provide biomaterials engineering development services based on Fucoidan, Carrageenan, and others. If you have any needs in biomaterial preparation, you can contact us at any time to inform your needs.