Properties
Description
Pemetrexed-PEG-chitosan (1 kDa, 98%) with antifolate drugs requires folate-deficient storage. Multiple reconstitutions reduce thymidylate synthase inhibition.
Molecular Weight
PEG: 1 kDa
Form
Solid or viscous liquid
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Stability
It is stable under its storage temperature.
Quality Level
Research level
Applications
The pH-sensitive chitosan framework in Pemetrexed-PEG-chitosan protects payloads during systemic circulation.
Storage
Store at -20°C, protect from light and moisture.