Cosmetic-grade Seaweed Oligosaccharide Ingredient Production Service

Home
Services
Marine Biomolecule Production Service
Industrial-grade Seaweed Oligosaccharide Ingredient Production
Cosmetic-grade Seaweed Oligosaccharide Ingredient Production Service

Cosmetic-grade Seaweed Oligosaccharide Ingredient Production Service

Overview

Seaweed oligosaccharides are low molecular weight carbohydrates obtained through the depolymerization of high molecular weight seaweed polysaccharides (such as alginate, fucoidan, carrageenan, and ulvan). This reduced size enhances their bioavailability, water solubility, and crucially, their specific biological activities, making them superior active ingredients for advanced skincare formulations. CD BioGlyco specializes in providing end-to-end, customized production services, ensuring our clients receive meticulously characterized, high-purity seaweed oligosaccharides optimized for applications like anti-aging, moisturizing, photoprotection, and whitening product development.

Key Technologies

Enzymatic Approach: We utilize highly specific enzymes, such as alginate lyases, fucoidanases, carrageenases, and laminarinases, to precisely cleave glycosidic bonds, allowing us to control the final oligosaccharide chain length (degree of polymerization, DP) and chemical structure with unparalleled accuracy.
Downstream Processing: Post-hydrolysis, we utilize nanofiltration, activated carbon adsorption, and advanced chromatography to remove impurities such as proteins, monosaccharides, and residual salts, guaranteeing a homogenous, high-purity final product.

Custom High-Efficacy Seaweed Oligosaccharides for Next-Generation Skincare

CD BioGlyco offers customized solutions covering the entire spectrum of cosmetic applications for seaweed oligosaccharides, serving both as active raw materials and functional excipients. We meet our customers' specific cosmetic development needs, such as whitening, anti-aging, moisturizing, and photoprotection.

Seaweed Oligosaccharides as Active Raw Materials

We provide high-purity seaweed oligosaccharide fractions tailored for specific dermatological endpoints, including:

Cosmetic Application	Target Seaweed Oligosaccharide	Key Bioactivity
Whitening Product	Fucooligosaccharides, Carrageenan oligosaccharides (COS)	Tyrosinase inhibition, anti-melanogenic effects, and reducing hyperpigmentation.
Anti-Aging and Anti-Wrinkle Product	Laminarin oligosaccharides, Alginate oligosaccharides (AOS)	Stimulation of collagen and elastin synthesis, suppression of Matrix Metalloproteinase (MMP) expression, and minimizing elastase activity.
Intense Moisturizing/Hydration Product	Ulvan oligosaccharides, Alginate oligosaccharides	High water-binding capacity, aiding in the formation of the skin's natural moisturizing factor (NMF), enhancing skin barrier function.
Photoprotection & Anti-Inflammation Product	Fucoidan oligosaccharides	UV filtering properties (MAAs), scavenging reactive oxygen species (ROS), reducing inflammatory markers, and preventing photoaging.

Seaweed Oligosaccharides as Excipients or Additives

Beyond active ingredients, CD BioGlyco's seaweed oligosaccharides dramatically improve the functional performance and textural quality of a cosmetic formulation:

Rheological and Textural Enhancement: Low molecular weight alginate and carrageenan derivatives are incorporated as superior thickening agents, gelling agents, or stabilizers, providing desired sensorial features and high stability to creams, lotions, and masks.
Emulsification and Delivery: Certain seaweed oligosaccharides are used to improve the stability of complex emulsions, aiding in the controlled delivery of other active ingredients into the skin's deeper layers, thereby enhancing overall product effectiveness.
Safety and Compatibility: Our highly purified seaweed oligosaccharides exhibit low cytotoxicity and low allergen content, making them ideal, safe, and efficient carriers or co-ingredients in sensitive skin or cosmeceutical formulations.

Workflow

Workflow for cosmetic-grade seaweed oligosaccharide ingredient production. (CD BioGlyco)

Publication Data

DoI: 10.3389/fnut.2022.945804

Journal: Frontiers in Nutrition

IF: 5.1

Published: 2022

Results: This article focuses on the preparation, purification, structural characterization, and biological activities of high-value laminaran oligosaccharides derived from the brown alga Laminaria digitata. The researchers obtained laminaran oligosaccharides with varying degrees of polymerization (DP 2–5) via partial acid hydrolysis of laminaran, and used fast protein liquid chromatography coupled with a refractive index detector (FPLC-RID), enabling automated and efficient isolation of pure laminaran oligosaccharides. Structural characterization confirmed the main structure of laminaran oligosaccharides as β-D-Glcp-(1→3)-β-D-Glcp linkages, corresponding to laminaribiose (DP2), laminaritriose (DP3), laminaritetrose (DP4), and laminaripentaose (DP5). Biological activity tests showed that laminaran oligosaccharides exhibited concentration-dependent antioxidant effects, with DP5 demonstrating the strongest scavenging activity against DPPH and ABTS radicals.

Fig.1 The chromatograms of laminaran oligosaccharide separated. (Cheong, et al., 2022)

Applications

High-End Anti-Aging Product Development

Serums, night creams, and boosters targeting fine lines and wrinkles by promoting dermal matrix protein synthesis.

Whitening and Brightening Cosmetic Development

Spot treatments, masks, and day creams formulated to address hyperpigmentation and uneven skin tone.

Barrier Repair Formulation Development

Moisturizers, lotions, and ampoules designed to replenish the NMF and fortify the skin barrier.

Sun Care and Post-Sun Repair Development

Products leveraging the photoprotective and anti-inflammatory properties of MAA-rich seaweed oligosaccharides for UV defense and soothing irritated skin.

Advantages

Customization on Demand

We offer complete control over the final product's specifications, including the degree of polymerization, sulfation patterns, and monosaccharide composition. Whether you need an anti-melanogenic fucooligosaccharide or a collagen-boosting laminarin derivative, our service is entirely tailored to your project.

Robust Quality and Safety Profile

Our commitment to high-purity isolation and rigorous testing ensures product quality. Every batch comes with a detailed Certificate of Analysis, confirming structure and purity.

Unrivaled Specificity and Purity

Our enzymatic approach guarantees structurally uniform oligosaccharides, providing a level of quality and batch-to-batch consistency unattainable through traditional chemical hydrolysis.

Frequently Asked Questions

Can you help us select the best type of seaweed for our anti-aging product?

Absolutely. Our scientific team consults with you to match the targeted biological mechanism (e.g., collagen boosting vs. antioxidant defense) with the optimal algal source and corresponding oligosaccharide structure.

What is the minimum quantity order for a custom oligosaccharide?

We offer flexible scaling, starting with small laboratory-scale batches (e.g., gram quantities) for initial formulation testing, right up to multi-kilogram production. Let's discuss your specific needs!

How stable are your oligosaccharides in a typical cosmetic formulation?

Due to their highly purified and stable structure, our seaweed oligosaccharides show excellent thermal and pH stability. We provide detailed stability testing reports to ensure formulation success.

Customer Review

"The quality and purity of the fucoidan oligosaccharide they supplied were exceptional, and the molecular weight consistency was perfect for achieving optimal skin penetration. The transition from pilot batch to large-scale production was seamless, and their team's expertise is unmatched in the field."

-M.J., Head of R&D, Premium Cosmeceuticals

"The customized alginate oligosaccharide exceeded our expectations, not only improving the texture but also providing a quantifiable boost to the product's overall moisturizing capacity. They deliver a multi-functional excipient that aligns perfectly with our 'active formulation' philosophy."

-A.W., Product Development Manager, Specialty Skincare

"We were impressed by their commitment to minimal solvent usage and high yields. A true, reliable partner in both science and compliance."

-D.C., Chief Procurement Officer, Natural Ingredients Supplier

Associated Services

Marine Carbohydrate Characterization

(CD BioGlyco)

Marine Glycoenzyme Development

(CD BioGlyco)

Marine Glycoconjugate Development

(CD BioGlyco)

CD BioGlyco is your definitive partner for the development and large-scale supply of high-purity, structurally defined seaweed oligosaccharides. Our unique blend of proprietary enzymatic technology, rigorous quality control, and deep scientific consultation is specifically designed to accelerate your cosmetic innovation, guaranteeing ingredients that are both efficacious and sustainable. Please feel free to contact us to tailor a production strategy that aligns perfectly with your product development goals and market vision.

Reference

Cheong, K.; et al. Preparation and structure characterization of high-value Laminaria digitata oligosaccharides. Frontiers in Nutrition. 2022, 9: 945804. (Open Access)

For research use only. Not intended for any clinical use.

Related Services

Services