Discover the Mysteries of Marine Crasseride
As a Marine Biomolecule Production company, CD BioGlyco is committed to exploring and utilizing Marine Glycolipid to add to our client's projects. Crasseride is a five-membered cyclitol glycolipid that is isolated from the sponge of Pseudoceratina crassa. Through a rigorous production quality system, our lab provides crasseride with excellent biological activity for various applications.
Pretreatment of Raw Materials
All sponges are collected, cleaned, and cryopreserved by our professional bio-researchers.
Extraction and Isolation
CD BioGlyco provides a reliable organic solvent extraction service using MeOH/toluene solutions. Extracts are extracted several times with trichloromethane and then concentrated to obtain a crude extract. Our lab combines medium-pressure liquid chromatography (MPLC) on silica gel and high-performance liquid chromatography (HPLC) on silica columns to separate target components.
- Purity testing: For purified samples, we use HPLC and thin-layer chromatography (TLC) to test their purity.
- Structural analysis: Combining mass spectrometry (MS), infrared spectroscopy (IR), and nuclear magnetic resonance (NMR), we provide accurate structural analysis services. Our researchers have accumulated extensive experience in spectral analysis to quickly analyze each compound. Our analytical reports contain specific structural inferences and multi-level mass spectrometry data to support your project.
Publication Data
Journal: Marine Drugs
Published: 2018
IF: 4.9
Results: In this article, the authors discuss the structural and biological evaluation of crasserides from the Caribbean sponge Pseudoceratina crassa (family Dysideidae). Its stereochemistry was determined by NMR spectroscopy. Moreover, an antifeedant assay showed that crasserides are good potent feeding deterrents.
Fig.1 Structures of the crasserides. (Cheng-Sánchez & Sarabia, 2018)
Applications
- Antifeedant activity: Crasseride has significant antifeedant activity and can be used to develop natural feeding deterrents of marine origin.
- Nucleoside intermediate development: Crasseride can be used as an intermediate in the synthesis of nucleoside carbocyclic analogs due to its structural similarity to furanosides.
- Crasseride provides valuable value information for the deep exploitation of marine glycolipids and promotes the exploitation of marine resources.
Advantages of Us
- Our researchers strictly control every step of production including, but not limited to, refrigerated transportation of raw materials, liquid phase separation gradients, and structural characterization.
- Depending on the samples to be separated, the column packing is carefully selected and compared by our specialized operators.
- All data analysis reports will be synchronized to the client's mailbox for the first time.
Frequently Asked Questions
What characterizes the structure of crasseride?
The structure of crasseride is similar to monogalactosyldiacyl-glycerol but differs in that crasseride contains an O-1-alkyl group instead of an O-1-acyl group. Most importantly, the sugar unit is substituted with a five-membered cyclitol, attached to O-3 with an ether bond.
Which marine sponges is crasseride found in?
Crasseride can be isolated from these sponges: Siphonodictyon coralliphagum, Verongula gigantea, Ectyoplasia ferox, Aplysina fulva, Plakortis simplex, Aplysina cauliformis, Agelas longissima, Neofibularia nolitangere, Agelas conifera, Agelas dispar, and Agelas clathrodes.
With many years of experience in the production of glycolipids, CD BioGlyco has always maintained a leading position in the production of crasseride and is committed to providing our clients with high-quality crasseride. We provide our clients with the most satisfactory and efficient production solutions without destroying the physiological activity of crasserides. Please feel free to contact us, we are always waiting for you!
Reference
- Cheng-Sánchez, I.; Sarabia, F. Chemistry and biology of bioactive glycolipids of marine origin. Marine Drugs. 2018, 16(9): 294.
