Empowering Innovation with Discoside Production Excellence
Discoside is a naturally occurring inositol-containing glycolipid compound with multiple chiral carbons and multiple hydroxyl groups that can be isolated from sponges. It is a compound containing diterpene glycoside, which has properties that include anti-tumor and anti-inflammatory effects. CD BioGlyco provides a comprehensive range of Marine Glycolipid Production Services, including the production of Marine Glycosphingolipid, Marine Glycoglycerolipid, and Marine Atypical Glycolipid. This includes our specialized discoside manufacturing services.
Discoside Extraction
We start by thawing the sponge samples and recording their weight when wet, as well as their excluded volume. Next, the samples are freeze-dried and treated with organic solvents at room temperature for extraction. The resulting extracts are then separated using liquid-liquid partitioning, employing a system such as water and dichloromethane (DCM). The concentrated organic phase (DCM phase) is subsequently chromatographed on a reverse phase C18 column, with elution achieved using a water/methanol solution to isolate marine glycolipids. Finally, the isolated compounds are quantified using high-performance liquid chromatography (HPLC-UV).
Discoside Characterization
Our experts use nuclear magnetic resonance (NMR) technology to help you determine the molecular structure and composition of glycolipids, including information on how and where the sugar and fatty acid groups are connected. Mass spectrometry (MS) allows us to determine the molecular weight and molecular formula of glycolipids, as well as detect possible impurities. Infrared spectroscopy (IR) is employed for the analysis of functional groups and chemical bonds in glycolipids to ascertain their structural composition. At the same time, our experts perform thermal analysis of the products to study the thermal properties of the glycolipids such as thermal stability and thermal decomposition behavior.
Publication Data
Journal: Marine Drugs
Published: 2011
IF: 4.9
Results: This article focuses on a review of the literature on Lithistida natural products since 2000. The article mentions a variety of natural products including microsclerodermins, scleritoderma nodosum, isomotuporins, mutremdamide A, perthamides, koshikamides, swinhoeiamide A, chemicalyculin A, bitungolides and discoside. The first discovery of discoside in Discodermia dissoluta is significant because it is the first time a compound like this has been found in marine sponges. A similar compound was previously only found in various strains of Propionibacterium.
Fig.1 The chemical structure of discoside. (Winder, et al., 2011)
Applications
- Discoside can be used in the pharmaceutical field as a natural drug candidate compound to explore its potential use in the study of related diseases.
- Discoside is used for formulation development in cosmetics and skin care products because of its ability to promote skin health and moisturization.
- Discoside has antiviral and antifungal activity and can be used as a pesticide or plant protectant to protect crops from viruses and fungi.
Advantages
- We help you extract your target compounds efficiently and achieve high yields and purity.
- Our extraction technology excels in preserving the integrity of the ingredients and minimizing any potential damage to them.
- Our extraction technology can be applied to a wide range of plant materials to extract different kinds of target components with high applicability.
Frequently Asked Questions
What is discoside?
Discoside is a compound that is a diterpene glycoside component derived from marine organisms. It is commonly present in marine organisms like sponges and corals. Discoside is a bioactive substance that possesses anti-inflammatory and anti-tumor properties, among other effects. It is a biologically active compound with anti-tumor and anti-inflammatory properties.
How to assess the safety and toxicity of discoside?
Safety and toxicity assessments for discoside can typically include the following: acute toxicity studies, subchronic toxicity studies, studies of long-term exposure, and chronic toxicity. These assessments can be conducted through a variety of methods including experimental animal models, cell culture experiments, and human clinical trials.
CD BioGlyco has extensive experience in utilizing advanced purification methods to produce discoside from marine sources. We offer customized solutions for research and development needs across a range of industries. Feel free to contact us with any inquiries.
Reference
- Winder, P.L.; et al. Natural products from the Lithistida: a review of the literature since 2000. Marine Drugs. 2011, 9(12): 2643-2682.
