Unleash Innovation with Ieodoglucomide Production
Ieodoglucomide is a glycolipid of marine origin with biological activity. It is a linear glycan synthesized from sodium bicarbonate and oxygen along the cytoplasm of natural secretory appendages and could have a wide range of potential applications in biomedicine. CD BioGlyco provides top-notch Marine Biomolecule Production Services to our esteemed clients across the globe. With extensive expertise in manufacturing a wide range of Marine Glycolipid, such as Marine Glycosphingolipid, Marine Glycoglycerolipid, and marine atypical glycolipids, we deliver high-quality products to meet our clients' diverse needs. Our ieodoglucomide production service includes but is not limited to the following.
Production
We synthesize the target molecules ieodoglucomide through a series of chemical reactions. First, we utilize an esterification reaction to combine D-glucose, succinic acid, and L-valine. Then, we proceed with cross olefination reaction to further modify the structure of the molecules. After that, reduction is carried out to achieve the desired chemical properties. Subsequently, debenzylation is performed to remove benzyl groups from the molecules. Finally, alcoholysis is used to complete the synthesis process.
We utilize a range of techniques for extracting ieodoglucomide, such as solvent extraction, supercritical fluid extraction (SFE), and solid phase extraction. SFE is a relatively new extraction method that utilizes certain gases close to the critical point that exhibit the properties of a liquid and are soluble. Our most commonly used supercritical fluid is carbon dioxide (CO2), which can be used in place of non-polar organic solvents such as hexane and methylene chloride for extraction of lipophilic components. We also make CO2 extract hydrophilic components by adding modifiers such as methanol. Solid phase extraction is our more common method of separation and purification using normal or reversed phase silica gel (C-18). After the extraction technique, we use high-performance liquid chromatography (HPLC) to separate and analyze the final purified compounds.
Characterization
The main methods we use to characterize the products include UV-Vis spectroscopy, infrared spectroscopy (IR), bioautography, paper diffusion, and microdilution. One of the methods utilized is UV-Vis spectroscopy, which is employed to identify the peak absorption wavelength and absorption coefficient of the substance at a particular concentration. IR is used to analyze the structure of the product while bioautography is used to detect the activity of the product. Additionally, paper diffusion is used to find the active compounds in crude extracts or isolates, and microdilution is used to determine the minimum inhibitory concentration of the product.
Publication Data
Technologies: Machine learning
Journal: Marine Drugs
Published: 2021
IF: 4.9
Results: This article focuses on marine microbe-derived antibiotics and biosurfactants as potential new drugs to combat catheter-associated urinary tract infections (CAUTIs). The authors isolated two unique glycolipid peptides, ieodoglucomides 1 and 2, from the marine Bacillus licheniformis 09IDYM23. They are described as medium antimicrobial molecules. The successful production of ieodoglucomides A and B has been achieved by researchers using a high-efficiency method with per-O-TMS glucosyl iodide, indicating their potential for use in industrial applications.
Fig.1 Chemical structure of ieodoglucomides. (Zhang, et al., 2021)
Applications
- Due to their bioactive properties and compatibility with living organisms, ieodoglucomides are utilized in a broad spectrum of research for drug development and biomedical engineering.
- Ieodoglucomides is a cell culture medium component commonly used in biotechnology and biomedicine, being used to provide the nutrients needed by cells.
- Ieodoglucomides are materials with good biocompatibility and drug carrier capabilities and therefore are widely used in drug delivery systems
Advantages
- We have our R&D team, which constantly improves the production process, increases production efficiency, and develops new technologies to stay ahead in the market.
- Our experienced team in charge of ieodoglucomide production has professional skills and knowledge to ensure the stability of the production process and quality control.
- We provide customized production services according to clients' needs, including bulk production, packaging, and distribution services to meet their different needs and market requirements.
Frequently Asked Questions
How is the stability of ieodoglucomide?
The stability of ieodoglucomide may be influenced by various factors, including environmental circumstances, storage techniques, and duration. Generally speaking, the ideal storage conditions are kept in a dry, cool, and light-avoiding environment, which helps maintain its stability.
What is its role or function in nature?
Ieodoglucomide is an alkaloid derived from marine organisms. In nature, ieodoglucomide may play a defensive role, helping marine organisms to defend themselves against natural enemies or pathogens. In addition, research also suggests that ieodoglucomide may have potential medicinal value for cancer and other diseases, as it exhibits certain biological activities and pharmacological properties.
CD BioGlyco has extensive experience in producing marine-derived ieodoglucomide through the use of advanced purification techniques. We offer customized solutions for the specific R&D requirements of our clients across various industries. If you have any inquiries, please feel free to contact us!
Reference
- Zhang, S.; et al. Marine microbial-derived antibiotics and biosurfactants as potential new agents against catheter-associated urinary tract infections. Marine Drugs. 2021, 19(5): 255.
