Your Partner in Premium Clathroside Production Services
One group of glycolipids does not fit into the traditional classification of glycolipids, which includes triglycerides, glycosphingolipids, and isoprenoid glycosides. These compounds are composed of a sugar group attached to the hydroxyl group of a fatty alcohol or hydroxy fatty acid, or the carboxyl group of a fatty acid. Based on our many years of experience in Marine Glycolipid Production, CD BioGlyco offers you comprehensive Marine Atypical Glycolipid Production Services, which include our professional clathroside production services.
Clathroside Extraction
First, we freeze the samples containing clathrodes and mix them using methanol. Then, we extract clathrodes using systems such as methanol and a mixture of methanol/chloroform and divide the extract into an organic phase and an aqueous phase. Subsequently, we concentrate the organic phase and subject the total fat-soluble extract to reversed-phase chromatography chromatography, using a gradient elution of water/methanol and chloroform. Silica gel column chromatography is then performed using a gradient of hexane/ethyl acetate to obtain fractions containing formylated clathrosides. Acetylated clathrosides are obtained after subjecting these fractions to an acetate anhydride reaction. Finally, normal-phase high-performance liquid chromatography (HPLC) is performed using a gradient of n-hexane/ethanol to isolate the clathrosides and subject these compounds to a deacetylation reaction to obtain the different clathrosides.
In addition, we also utilize state-of-the-art equipment and technology to aid in the extraction of clathroside. These methods include but are not limited to supercritical fluid extraction and microwave-assisted extraction.
Clathroside Characterization
We utilize 1H and 13C nuclear magnetic resonance (NMR) spectra for compound analysis to determine their structure and composition. Additionally, high-resolution electrospray ionization mass spectrometry (ESI-MS) spectra are employed for analyzing the molecular formulas of the chemicals. Optical spinosondes are also utilized for the optical rotation determination of cathodes.
Publication Data
Technology: Natural compound isolation
Journal: Marine Drugs
IF: 5.4
Published: 2018
Results: This article provides a comprehensive overview of bioactive glycolipids derived from marine sources. It delves into the various biologically active glycolipid compounds that have been found to exhibit anti-tumor, anti-viral, and anti-inflammatory properties. Furthermore, the article discusses in detail the synthetic methods and structure-activity relationships of these compounds, shedding light on their potential for pharmaceutical applications. In addition, the article also offers insights into the structure and origin of clathrosides, further expanding the understanding of these bioactive compounds. The inclusion of studies on clathrosides adds depth to knowledge of their biological activities and potential therapeutic uses.
Fig.1 The chemical structure of clathrosides. (Cheng-Sánchez & Sarabia, 2018)
Applications
- Clathrosides are widely used by researchers in the field of drug discovery for the development of drugs related to diseases such as cancer, cardiovascular diseases, and inflammatory diseases.
- Clathrosides have antioxidant, preservative, and flavor-enhancing properties and are used in the research and development of food formulations to extend the shelf life of food products and improve their quality and taste.
- Clathrosides are widely used in the development of cosmetic formulations to help maintain healthy and youthful skin.
Advantages
- Our production technology enables efficient extraction and purification of clathrosides, resulting in a highly pure product, which is conducive to ensuring its medicinal effects and safety.
- We use gentle clathrosides production technology to maximize the stability and activity of its medicinal ingredients.
- We are constantly developing and optimizing our biotechnology and bioengineering techniques, such as fermentation, to provide you with high yields and purity of clathrosides.
Frequently Asked Questions
How stable are clathroside during extraction?
Clathrosides are usually stable and can maintain their activity and potency during the extraction process. However, stability during extraction may be affected by factors such as choice of extraction method, temperature, pH, and light.
How should clathroside extract be stored to maintain its activity?
Clathroside extracts should be stored in a dry, cool, protected environment away from direct sunlight and they should be stored in sealed glass bottles or plastic containers, avoiding contact with metals or other reactive materials.
CD BioGlyco is a leading company that offers advanced marine biomolecule production services which includes our high-quality clathroside production service. Our team of researchers is highly skilled and produces innovative products, as well as offers marine carbohydrate characterization services. If you are interested in learning more about our company, please don't hesitate to contact us.
Reference
- Cheng-Sánchez, I.; Sarabia, F. Chemistry and biology of bioactive glycolipids of marine origin. Marine Drugs. 2018, 16(9): 294.
